We all have heard about Erectile dysfunction, but are we aware about what Erectile dysfunction actually is?
Erectile dysfunction is a condition that prevents one from getting or keeping an erection during sex. Erectile dysfunction may be classified as organic, psychogenic, or a mixture of both. Organic includes erectile dysfunction caused by neurologic factors, penile structure, vascular abnormalities, or medications. Psychogenic erectile dysfunction may be associated with several factors, but is frequently linked to performance anxiety, lack of libido, or other psychiatric conditions, such as depression. Many men are still uncomfortable talking about such diseases. Why are we ashamed of a condition that has nothing to do with our ability? One should never be ashamed of anything that can be treated. Research suggests that around 30-50 million men in the US have ED. ED is specifically seen in older men. Incidence of Erectile dysfunction increases with age. Men aged 18-59 years have an incidence of erectile dysfunction of 10%. At the age of 40, at least 40% of men are facing the issue, while 70% of the men report the problem by the age of 70.
Advances in medical science, combined with greater openness towards men’s health has paved a way towards better, safer and effective options for the treatment of the issue. Among these advancements, Avanafil has been showing remarkable progress in reshaping ED.
History of Avanafil
Avanafil was approved for ED treatment by the FDA on April 27, 2012 and by the EMA on June 21, 2013. In 2011, Vivus submitted an NDA for the drug to FDA. It was invented at a Japanese Company, Mitsubishi Tanabe Pharma, formerly known as Tanabe Seiyaku Co., and licensed to Vivus Inc., which partnered with Menarini Group to commercialise Spedra (brand name of Avanafil) in over forty European countries, including Australia, and New Zealand. Metuchen Pharmaceuticals obtained exclusive rights within the United States. It is sold under the brand name Stendra in the US.
What is Avanafil?
Avanafil is a Phosphodiesterase-5 (PDE5) inhibitor used for the treatment of ED. It is a prescription medication specifically used in elderly men. It helps in achieving and maintaining an erection that is required during sexual activity. Avanafil is an active ingredient present in medications such as Avaforce, Avanair, Avana.
How does it work?
- When a man is sexually aroused, a chemical called Nitric Oxide (NO) is released in the body.
- NO helps in the relaxation of the muscles in the penile blood vessels.
- This eventually causes increased blood flow.
- Avanafil blocks the action of PDE5 inhibitors that are responsible for the breaking of NO, which increases the blood flow to the penis since higher levels of NO are maintained in the body.
- Improved blood flow helps to achieve and sustain better erection.
Therapeutic Uses and Benefits:
- Treatment of ED
- The main use of Avanafil is for the treatment of ED which can be caused either by physical, psychological or both factors.
- Confidence booster
- Since there is no stress about erection, it will eventually increase the confidence while sexually active.
- Faster Onset of Action
- Avanafil can work as quickly as in 15-20 minutes compared to other ED medications like Sildenafil, Vardenafil.
- Improved Erection Quality and Duration
- Avanafil often helps men to achieve stable and firm long-lasting erection with effects lasting up to 6 hours.
- Better Tolerability
- According to studies associated with clinical trials, there are very few side-effects that can be seen due to Avanafil compared to other PDE5 inhibitors.
- Variable dosing
- The medication can be taken with or without a meal.
- Customized Treatment
- If needed, the doctor can adjust the dosing according to the patient’s needs and requirements, tailoring to the situation.
- Safety
- When used according to the prescribed dose, it is usually safe and with lesser side-effects.
Side-Effects and How to work on them?
Common Side-effects:
- Headache- This is the side-effect that is observed at the maximum as there is increased blood flow in the body
How to manage it:
- Hydrate yourself
- Rest in quiet and dim environment
- Take a nap if required
- Avoid alcohol
- If headache is persistent, consult your physician and take a mild painkiller
- Stuffed nose
How to manage it:
- Saline nasal sprays can be used
- Stay hydrated
- Use a decongestant if prescribed
- Lightheadedness
How to manage it:
- Sit or lay down quickly to avoid any other mishap
- Do not drive or use machinery
- Have something sweet or drink water
- Facial Flushing
How to manage it:
- Make sure to have the medication on empty stomach to decrease the sensation
- Stay in a cool room
- Avoid hot showers
- Limit spicy food during the dosing period
- Back pain or Muscle Ache
How to manage it:
- Adequate rest is appreciated
- Cold or hot compressions
- OTC painkillers if prescribed by the physician
Less Common Side-effects:
- Vision problems
- Prolonged Erections
- Chest pain
- Shortness of breath
In all these cases, make sure to consult a healthcare provider at the earliest.
Contraindications:
Medications:
Avanafil should be avoided with the following medications:
- Nitrates: Any medications consisting of any form of nitrate or nitric acid are contraindicated with Avanafil.
- Guanylate cyclase stimulators: Drugs such as riociguat which is used to treat pulmonary hypertension in the arteries should be avoided.
- Strong CYP3A4 inhibitors: Certain antifungals (e.g. ketoconazole, itraconazole), HIV protease inhibitors (e.g. ritonavir, indinavir), antibiotics and Nefazodone can cause unsafe levels of Avanafil in the blood stream if taken together.
Health Conditions:
Avanafil is generally not recommended or requires extreme caution and medical supervision in individuals with certain medical histories:
- Cardiovascular issues:
- Recent heart attack (within the last 3-6 months)
- Recent stroke (within the last 6 months)
- Severe heart problems
- Hypertension
- Hypotension
- Life-threatening arrhythmias or unstable angina
- Hypersensitivity: Allergic reactions to Avanafil or any other drug ingredients.
- Eye disorders: Individuals with a history of optic neuropathy or rare inherited eye diseases.
- Severe hepatic or renal impairment.
- Blood cell disorders:
- Sickle cell anaemia
- Multiple myeloma
- Leukaemia
- Anatomical deformation of the penis
Consulting a physician before selecting your daily medication should be practiced on a regular basis.
Precautions and Warnings:
- Avoid excessive consumption of alcohol.
- Grapefruit or grapefruit juice should be avoided with the medication.
- Avoid driving after using the medication.
- Avanafil does not give protection against Sexually transmitted infections.
- Avoid using Avanafil with Nitrate medications.
- Inform your doctor about all the medical history to avoid risks in future.
- Avanafil is to be used for adult men only.
- Use with caution if you suffer with hypotension as it can lower blood pressure.
- Seek immediate help if you encounter vision loss due to Avanafil.
Myths vs. Reality: Clearing the Confusion Around ED Treatment
Misconceptions around erectile dysfunction and its treatment remain widespread despite growing awareness around this topic.
Myth: Only Older men are prone to Erectile dysfunction.
Reality: All age groups have a chance of getting affected by ED as it is often linked with stress, lifestyle, or other health conditions.
Myth: ED medications that have faster onset of action often show more side-effects.
Reality: Selective treatments like Avanafil are designed to target erectile function more precisely, improving tolerability for many users.
Myth: Digital spaces are less trustworthy
Reality: Credible digital health platforms that prioritize safety and education can offer dependable access when operated responsibly.
Myth: ED treatment is only needed temporarily
Reality: For many men, erectile dysfunction is a recurring condition. Consistent, medically guided treatment can help manage symptoms more effectively than sporadic or unplanned use.
Myth: Long-term use of ED medications are unsafe
Reality: Many ED treatments are considered safe for ongoing use when taken under appropriate medical supervision and prescription. Regular health evaluations help ensure continued suitability.
Myth: Online ED treatments are always risky or counterfeit
Reality: The risk lies not in online access itself, but in choosing unreliable sources. Trusted platforms like edpillsforever.com emphasize on authenticity, transparency, and patient education to support safe access.
The Growing Need for Trusted Online Health Platforms
Online pharmacies and healthcare platforms are gaining a lot of trust and interest as they are increasing day-to-day. Authenticity, safety, rules and regulations are the ones that matter the most which has made the access to the treatments more suitable due to the digital growth. Today, patients are not only seeking drugs- they are looking for integrity.
A trusted electronic health platform offers consumers more than just the list of products. It provides:
- Accurate and reliable information
- Clarity regarding source and quality
- Directions for safe use of the medication
- Trustworthy user experience
Since there is rising consciousness around ED, electronic platforms that sell ED medications such as Avanafil, sildenafil, etc take over the responsibility to make sure the patients receive all the support, information, protection and guidance.
Why Education Matters as Much as Access
Perhaps one of the most underappreciated sources of ED is its realm for the education on men’s sexual health. Men often differ in treatment because of misguided notions and hopes. ED is a health issue, is what is taught by a responsible electronic platform rather than expressing it as a health challenge.
Educational content surrounding Avanafil helps patients understand:
- Mechanism of medication?
- Who may it be suitable for?
- Why does medical consultation matter?
- How lifestyle and health factors affect results?
By focusing on education, trusted platforms like https://edpillsforever.com allow users to make rational rather than impulsive decisions.
Promoting Safety in a Crowded Digital Market
Although there is a lot of competition on the internet between the sites dealing with ED medications, not all operate with the same level of standards. Counterfeit products, misleading claims, and shortfall of transparency have been some of the major concerns. Platform credibility has thus become an important part that helps patients to decide.
edpillsforever.com focus on:
- Providing genuine medicines only
- Offering descriptive product information
- Stringent quality standards are followed
- Supporting professional medical advice
- Privacy focused user experience
Why Has Online Purchase of Cenforce Gained Popularity?
In recent years, there has been an escalation in the demand for Cenforce through online platforms. Several factors contribute to this trend:
- Complete Privacy for sensitive health concerns to avoid embarrassment
- Avoid regular visits to the clinic and order from your comfort space.
- Clear and reliable information at your fingertips
- Upfront pricing with affordable prices
- Easier availability of medication for people living in remote and interior regions.
For many men, the ability to research their condition, understand treatment options, and consult professionals online reduces anxiety and encourages timely intervention.
Transparency Builds Confidence
Trust is often associated with how the platform conveys about what the medication can and cannot do. Guidelines regarding the treatment, use, and consultation regarding the treatment will make users feel well-informed, rather than coerced.
By that measure, it could be said that this transparency has other significant aspects that benefit both patients and the platform independently.
The Future of ED care
The demand for efficacious and resilient ED treatments like Avanafil is rising as men are becoming more concerned about their health. The future of this sector will be led by platforms that marry innovation with responsibility.
Education, authenticity, and patient-centric outlook are the one that distinguishes the normal platforms with the one that are focused on creating trustworthy sites. EDPillsForever reflects this progressive outlook that helps to create more clear and balanced conversation around men’s sexual health.
About the Platform
https://edpillsforever.com/ is a health-oriented digital platform committed to delivering precise, current medical information and responsible access to healthcare items. Placing a significant focus on patient education, safety, and transparency, the platform seeks to enable individuals to make knowledgeable health choices alongside qualified healthcare professionals.
Contact Details
Website: https://edpillsforever.com/
Number: +1(734)274-6420
References:
https://pubmed.ncbi.nlm.nih.gov/22973106/

